Selected Drugs Clear All
MultiCheck Results
- 4
Interactions
Monitor/Modify Tx |
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benazepril/hydrochlorothiazide
(generic) + Gammaplex
(immune globulin (human)) |
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Monitor/Modify Txbenazepril + immune globulin monitor renal fxn; use lowest immune globulin dose, concentration and infusion rate possible: combo may incr. risk of nephrotoxicity (additive effects) hydrochlorothiazide + immune globulin monitor renal fxn; use lowest immune globulin dose, concentration and infusion rate possible: combo may incr. risk of nephrotoxicity (additive effects) |
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benazepril/hydrochlorothiazide
(generic) + Kadian
(morphine sulfate) |
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Monitor/Modify Txbenazepril + morphine monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope (additive effects) hydrochlorothiazide + morphine monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope; may decr. hydrochlorothiazide efficacy (additive effects; antagonistic effects, opioids may induce antidiuretic hormone release) |
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Additional Considerations |
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immune globulin
in Gammaplex
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monitor renal function; nephrotoxicity risk may be higher with sucrose-containing immune globulins, may vary depending on route of administration |
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morphine
in Kadian
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use avoid combo with beverages or products containing ethanol and some morphine extended-release (ER) capsules; combo may incr. morphine release rate, levels, risk of adverse effects, including life-threatening overdose, decr. duration of efficacy |
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