Selected Drugs Clear All
MultiCheck Results
- 1
Interaction
Monitor/Modify Tx |
||
|
methocarbamol
(generic) + nalbuphine
(generic) |
||
Monitor/Modify Txmethocarbamol + nalbuphine monitor respiratory rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects) |
||
Additional Considerations |
||
|
adalimumab
in Humira
|
||
|
caution advised with narrow therapeutic index drugs; chronic inflammatory conditions may alter metabolic enzyme formation; tx with immune modulators may reverse this effect, resulting in altered levels of concomitant drugs |
||
|
nalbuphine
|
||
|
consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use |
||