Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Contraindicated |
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Uribel Tabs
(methenamine/ benzoic acid/ phenyl salicylate/ methylene blue/ hyoscyamine) + Virtussin DAC
(codeine/ pseudoephedrine/ guaifenesin) |
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Contraindicatedmethylene blue oral + codeine contraindicated w/in 14 days of methylene blue use; if urgent use, consider alternative, incl. buprenorphine or oxymorphone: combo may incr. risk of respiratory depression, serotonin syndrome (additive effects, methylene blue reversibly inhibits monoamine oxidase) Avoid/Use Alternativehyoscyamine + codeine avoid combo if antitussive use; otherwise, monitor respiratory rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, severe constipation, paralytic ileus, urinary retention (additive effects) Monitor/Modify Txhyoscyamine + pseudoephedrine monitor HR: combo may incr. risk of tachycardia (additive effects) |
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Additional Considerations |
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hyoscyamine
in Uribel Tabs
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caution advised with concurrent oral drugs requiring rapid onset; hyoscyamine delays gastric emptying, may alter absorption of concomitant oral drugs |
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codeine
in Virtussin DAC
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use |
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pseudoephedrine
in Virtussin DAC
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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