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Interaction Check

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Selected Drugs Clear All

  • remove domperidone
    generic
  • remove Virtussin DAC
    codeine/ pseudoephedrine/ guaifenesin

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face domperidone (generic) + Virtussin DAC (codeine/ pseudoephedrine/ guaifenesin)

Avoid/Use Alternative


domperidone + codeine

avoid combo if antitussive use; otherwise monitor respiratory rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment; may decr. domperidone efficacy (additive effects; antagonistic effects)

Additional Considerations

Smiley face Smiley face codeine in Virtussin DAC

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face pseudoephedrine in Virtussin DAC

add MAO inhibitor to Interaction Check if recent (14 days) use

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