Interaction Check

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Selected Drugs Clear All

MultiCheck Results - 2 Interactions

Monitor/Modify Tx
Focalin (dexmethylphenidate hydrochloride) + Reglan (metoclopramide)
Monitor/Modify Tx dexmethylphenidate + metoclopramide monitor BP, serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome, HTN (additive effects)
Caution Advised
Bimzelx (bimekizumab-bkzx) (bimekizumab) + Imuldosa (ustekinumab-srlf) (ustekinumab)
Caution Advised bimekizumab + ustekinumab caution advised: combo may incr. risk of serious infection (additive effects)
Additional Considerations
ustekinumab in Imuldosa (ustekinumab-srlf)
caution advised w/ narrow therapeutic index drugs; chronic inflammatory conditions may alter metabolic enzyme formation; tx w/ immune modulators may reverse this effect, resulting in altered levels of concomitant drugs
dexmethylphenidate in Focalin
serdexmethylphenidate is the prodrug of dexmethylphenidate; similar interactions anticipated add MAO inhibitor to Interaction Check if recent (14 days) use
bimekizumab in Bimzelx (bimekizumab-bkzx)
caution advised with narrow therapeutic index drugs; chronic inflammatory conditions may alter metabolic enzyme formation; tx with immune modulators may reverse this effect, resulting in altered levels of concomitant drugs