Interaction Check

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Selected Drugs Clear All

MultiCheck Results - 1 Interaction

Caution Advised
Qsymia (phentermine hydrochloride/ topiramate) + Sporanox (itraconazole)
Caution Advised topiramate + itraconazole caution advised: combo may decr. itraconazole levels, efficacy; may incr. topiramate levels, risk of adverse effects (hepatic metabolism induced; hepatic metabolism inhibited)
Additional Considerations
phentermine in Qsymia
add MAO inhibitor to Interaction Check if recent (14 days) use
topiramate in Qsymia
beverages or products containing ethanol are contraindicated within 6h of topiramate extended-release (ER) capsules administration; combo may incr. topiramate release rate, levels, risk of adverse effects, decr. duration of efficacy
itraconazole in Sporanox
itraconazole converted to active metabolite hydroxyitraconazole