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Interaction Check

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Selected Drugs Clear All

  • remove Simpesse
    levonorgestrel/ ethinyl estradiol
  • remove tazarotene topical
    generic
  • remove Vevye
    cyclosporine ophthalmic
  • remove Zanaflex
    tizanidine

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative
Smiley face Smiley face Simpesse (levonorgestrel/ ethinyl estradiol) + Zanaflex (tizanidine)

Avoid/Use Alternative

ethinyl estradiol (contraceptive) + tizanidine

use alternative or monitor BP, HR: combo may incr. tizanidine levels, risk of hypotension (including orthostasis, syncope), bradycardia, CNS depression, psychomotor impairment, other adverse effects (hepatic metabolism inhibited)

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