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Interaction Check

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Selected Drugs Clear All

  • remove Abrysvo
    respiratory syncytial virus vaccine (RSV)
  • remove bisoprolol/ hydrochlorothiazide
    generic
  • remove N-acetyl D-glucosamine
    glucosamine
  • remove Tecvayli (teclistamab-cqyv)
    teclistamab
  • remove Tenuate
    diethylpropion

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Abrysvo (respiratory syncytial virus vaccine (RSV)) + Tecvayli (teclistamab-cqyv) (teclistamab)

Monitor/Modify Tx


respiratory syncytial virus vaccine + teclistamab

if possible, vaccinate at least 2wk before starting teclistamab tx; otherwise, consider post-immunization titer check or revaccination after immunocompetence restored: combo may result in inadequate vaccine response (immunosuppressive effects)

Smiley face Smiley face bisoprolol/hydrochlorothiazide (generic) + Tenuate (diethylpropion)

Monitor/Modify Tx


bisoprolol + diethylpropion

monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

hydrochlorothiazide + diethylpropion

monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

Additional Considerations

Smiley face Smiley face diethylpropion in Tenuate

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face teclistamab in Tecvayli (teclistamab-cqyv)

caution advised with narrow therapeutic index drugs, especially during teclistamab initiation/titration and up to 7 days after first full tx dose or during/after CRS; teclistamab may incr. cytokine release leading to suppression of metabolic enzymes, causing incr. drug levels, risk of adverse effects

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