Interaction Check

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Selected Drugs Clear All

MultiCheck Results - 2 Interactions

Avoid/Use Alternative
Tofranil (imipramine) + Zurzuvae (zuranolone)
Avoid/Use Alternative imipramine + zuranolone use alternative or consider decr. dose of one or both drugs: combo may incr. risk of CNS depression, psychomotor impairment (additive effects)
Monitor/Modify Tx
Tofranil (imipramine) + Zicam Extreme Congestion Relief (oxymetazoline nasal)
Monitor/Modify Tx imipramine + oxymetazoline nasal monitor BP: combo may incr. risk of HTN (additive effects)
Additional Considerations
imipramine in Tofranil
add MAO inhibitor to Interaction Check if recent (14 days) use