Selected Drugs Clear All
MultiCheck Results
- 2
Interactions
Avoid/Use Alternative |
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Xyrem
(sodium oxybate) + Zoloft
(sertraline) |
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Avoid/Use Alternativeoxybate + sertraline use alternative or monitor respiratory rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, hypotension, syncope (additive effects) |
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Monitor/Modify Tx |
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Paxlovid
(nirmatrelvir and ritonavir) + Zoloft
(sertraline) |
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Monitor/Modify Txritonavir + sertraline monitor ECG: combo may incr. sertraline levels, risk of QT prolongation, cardiac arrhythmias, other adverse effects (hepatic metabolism inhibited) |
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Additional Considerations |
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nirmatrelvir
in Paxlovid
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patients on ritonavir- or cobicistat-containing HIV or HCV regimens may continue their tx as indicated |
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sertraline
in Zoloft
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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