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Interaction Check

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Selected Drugs Clear All

  • remove Cheratussin AC
    codeine/ guaifenesin
  • remove Fabhalta
    iptacopan
  • remove Flovent HFA
    fluticasone propionate inhaled
  • remove minoxidil
    generic
  • remove olanzapine
    generic

multicheck MultiCheck Results - 4 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Cheratussin AC (codeine/ guaifenesin) + olanzapine (generic)

Avoid/Use Alternative


codeine + olanzapine

avoid combo if antitussive use; otherwise, consider alternative or monitor respiratory rate, BP; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, severe hypotension (including orthostasis, syncope), severe constipation, paralytic ileus (including life-threatening), urinary retention (additive effects)

Monitor/Modify Tx

Smiley face Smiley face Cheratussin AC (codeine/ guaifenesin) + minoxidil (generic)

Monitor/Modify Tx


codeine + minoxidil

monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope (additive effects)

Smiley face Smiley face minoxidil (generic) + olanzapine (generic)

Monitor/Modify Tx


minoxidil + olanzapine

monitor BP: combo may incr. risk of hypotension, including orthostasis, syncope (additive effects)

Caution Advised

Smiley face Smiley face Fabhalta (iptacopan) + Flovent HFA (fluticasone propionate inhaled)

Caution Advised


iptacopan + fluticasone propionate

caution advised: combo may incr. risk of serious infection (additive effects)

Additional Considerations

Smiley face Smiley face codeine in Cheratussin AC

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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