Interaction Check

This page cannot be displayed because your browser has been configured to disable JavaScript, also known as "Active Scripting".Please change your settings and refresh the page.

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

MultiCheck Results - 3 Interactions

Monitor/Modify Tx
Cabometyx (cabozantinib) + Paxil CR (paroxetine)
Monitor/Modify Tx cabozantinib + paroxetine monitor bleeding s/sx: combo may incr. risk of GI or other bleeding, including life-threatening (additive effects, antiplatelet effects augmented by inhibition of platelet serotonin uptake)
Cabometyx (cabozantinib) + Zosyn (piperacillin/ tazobactam)
Monitor/Modify Tx cabozantinib + piperacillin monitor bleeding s/sx, especially w/ prolonged piperacillin tx and/or concomitant renal impairment: combo may incr. risk of GI or other bleeding, including life-threatening (additive effects)
Paxil CR (paroxetine) + Zosyn (piperacillin/ tazobactam)
Monitor/Modify Tx paroxetine + piperacillin monitor bleeding s/sx, especially w/ prolonged piperacillin tx and/or concomitant renal impairment: combo may incr. risk of bleeding, including life-threatening (additive effects, antiplatelet effects augmented by inhibition of platelet serotonin uptake)
Additional Considerations
paroxetine in Paxil CR
add MAO inhibitor to Interaction Check if recent (14 days) use