Selected Drugs Clear All
MultiCheck Results
- 5
Interactions
Monitor/Modify Tx |
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clomipramine
(generic) + Synthroid
(levothyroxine) |
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Monitor/Modify Txclomipramine + levothyroxine monitor BP, HR: combo may incr. risk of HTN, tachycardia, cardiac arrhythmias, CNS stimulation (additive effects) |
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clomipramine
(generic) + Xylocaine
(lidocaine) |
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Monitor/Modify Txclomipramine + lidocaine monitor BP: combo may incr. risk of seizures, hypotension, including orthostasis (additive effects) |
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Synthroid
(levothyroxine) + valproic acid
(generic) |
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Monitor/Modify Txlevothyroxine + valproic acid monitor thyroid fxn: combo may decr. thyroid hormone levels, efficacy (UGT induced) |
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Caution Advised |
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clomipramine
(generic) + valproic acid
(generic) |
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Caution Advisedclomipramine + valproic acid caution advised: combo may incr. risk of CNS depression, psychomotor impairment; may alter seizure control (additive effects; antagonistic effects, clomipramine may decr. seizure threshold) |
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valproic acid
(generic) + Xylocaine
(lidocaine) |
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Caution Advisedvalproic acid + lidocaine caution advised if seizure disorder use: combo may alter seizure control (antagonistic effects, lidocaine may decr. seizure threshold) |
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Additional Considerations |
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clomipramine
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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levothyroxine
in Synthroid
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monitor thyroid function more frequently when starting, adjusting, or stopping other drugs, including short-term therapies, OTC drugs, herbal supplements |
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