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Interaction Check

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Selected Drugs Clear All

  • remove Cortizone-10 Feminine Itch Relief
    hydrocortisone topical
  • remove Eylea
    aflibercept intravitreal
  • remove Methergine
    methylergonovine
  • remove sumatriptan
    generic
  • remove Tri-Linyah
    norgestimate/ ethinyl estradiol

multicheck MultiCheck Results - 5 Interactions

Smiley face Smiley face

Contraindicated

Smiley face Smiley face Methergine (methylergonovine) + sumatriptan (generic)

Contraindicated


methylergonovine + sumatriptan

contraindicated w/in 24h of use: combo may incr. risk of severe HTN, prolonged vasospasm, ischemia, serotonin syndrome (additive effects)

Monitor/Modify Tx

Smiley face Smiley face Eylea (aflibercept intravitreal) + Tri-Linyah (norgestimate/ ethinyl estradiol)

Monitor/Modify Tx


aflibercept + ethinyl estradiol (contraceptive)

monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)

aflibercept + norgestimate (contraceptive)

monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects)

Smiley face Smiley face Methergine (methylergonovine) + Tri-Linyah (norgestimate/ ethinyl estradiol)

Monitor/Modify Tx


methylergonovine + ethinyl estradiol (contraceptive)

monitor BP: combo may incr. methylergonovine levels, risk of ergot toxicity, severe vasospasm, ischemia, HTN, other adverse effects (hepatic metabolism inhibited, additive effects)

Smiley face Smiley face sumatriptan (generic) + Tri-Linyah (norgestimate/ ethinyl estradiol)

Monitor/Modify Tx


sumatriptan + ethinyl estradiol (contraceptive)

monitor BP: combo may incr. risk of HTN (additive effects)

Additional Considerations

Smiley face Smiley face sumatriptan

add MAO inhibitor to Interaction Check if recent (14 days) use

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