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Interaction Check

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Selected Drugs Clear All

  • remove nalbuphine
    generic
  • remove olaparib
    generic
  • remove S-adénosylméthionine
    SAMe

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face nalbuphine (generic) + S-adénosylméthionine (SAMe)

Avoid/Use Alternative


nalbuphine + SAMe

use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

Additional Considerations

Smiley face Smiley face nalbuphine

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

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