epocrates logo
epocrates logo
epocrates logo
  • 0

Interaction Check

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

  • remove chaste tree
    chasteberry (Vitex agnus-castus)
  • remove Chloraseptic Warming Sore Throat Lozenges
    benzocaine oropharyngeal
  • remove Clenpiq
    sodium picosulfate/ magnesium oxide/ citric acid
  • remove clozapine
    generic
  • remove Pavulon
    pancuronium

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Caution Advised

Smiley face Smiley face chaste tree (chasteberry (Vitex agnus-castus)) + clozapine (generic)

Caution Advised


chasteberry + clozapine

caution advised: combo may decr. clozapine efficacy (antagonistic effects, chasteberry exerts dopaminergic effects)

Smiley face Smiley face Clenpiq (sodium picosulfate/ magnesium oxide/ citric acid) + clozapine (generic)

Caution Advised


magnesium citrate + clozapine

caution advised, especially if magnesium citrate bowel prep use: combo may incr. risk of seizures (additive effects)

sodium picosulfate + clozapine

caution advised: combo may incr. risk of seizures (additive effects)

Additional Considerations

Smiley face Smiley face pancuronium in Pavulon

Discontinued in US

Smiley face Smiley face magnesium citrate in Clenpiq

separate administration from other oral drugs by at least 1h; magnesium citrate may decr. absorption of concomitant oral drugs

Smiley face Smiley face sodium picosulfate in Clenpiq

separate administration from other oral drugs by at least 1h; sodium picosulfate may decr. absorption of concomitant oral drugs

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information