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Interaction Check

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Selected Drugs Clear All

  • remove edoxaban
    generic
  • remove Incassia
    norethindrone
  • remove Loreev XR
    lorazepam
  • remove Necon 1/ 35
    norethindrone/ ethinyl estradiol
  • remove Primatene Tablets
    ephedrine

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Incassia (norethindrone) + Necon 1/35 (norethindrone/ ethinyl estradiol)

Avoid/Use Alternative


norethindrone (contraceptive) + norethindrone (contraceptive)

avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)

Monitor/Modify Tx

Smiley face Smiley face Loreev XR (lorazepam) + Necon 1/35 (norethindrone/ ethinyl estradiol)

Monitor/Modify Tx


lorazepam + ethinyl estradiol (contraceptive)

consider lorazepam dose adjustment: combo may decr. lorazepam levels, efficacy (mechanism unknown)

Smiley face Smiley face Necon 1/35 (norethindrone/ ethinyl estradiol) + Primatene Tablets (ephedrine)

Monitor/Modify Tx


ethinyl estradiol (contraceptive) + ephedrine oral

monitor BP: combo may incr. risk of HTN (additive effects)

Additional Considerations

Smiley face Smiley face ephedrine oral in Primatene Tablets

add MAO inhibitor to Interaction Check if recent (14 days) use

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