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Interaction Check

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Selected Drugs Clear All

  • remove Estrace Vaginal
    estradiol vaginal
  • remove Parcopa
    carbidopa/ levodopa
  • remove Zyprexa Zydis
    olanzapine

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Parcopa (carbidopa/ levodopa) + Zyprexa Zydis (olanzapine)

Monitor/Modify Tx


levodopa + olanzapine

monitor BP: combo may incr. risk of CNS depression, psychomotor impairment, hypotension, including orthostasis, syncope; may decr. efficacy of both drugs (additive effects; antagonistic effects)

Additional Considerations

Smiley face Smiley face levodopa in Parcopa

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and Crexont; combo may incr. levodopa release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face carbidopa in Parcopa

avoid combo with beverages or products containing ethanol and Crexont; combo may incr. carbidopa release rate, levels, risk of adverse effects, decr. duration of efficacy

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