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Interaction Check

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Selected Drugs Clear All

  • remove Mono-Linyah
    norgestimate/ ethinyl estradiol
  • remove Robitussin AC
    codeine/ guaifenesin

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Mono-Linyah (norgestimate/ ethinyl estradiol) + Robitussin AC (codeine/ guaifenesin)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + codeine

use alternative or monitor respiratory rate, withdrawal sx: combo may incr. codeine, alter active metabolite morphine levels, incr. risk of CNS and respiratory depression, psychomotor impairment, other adverse effects or decr. efficacy (hepatic metabolism inhibited, may alter production of active metabolite morphine)

Additional Considerations

Smiley face Smiley face codeine in Robitussin AC

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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