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Interaction Check

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Selected Drugs Clear All

  • remove boswellia (Boswellia serrata)
    common name
  • remove Methylin
    methylphenidate
  • remove Vicks DayQuil Cold & Flu
    acetaminophen/ dextromethorphan/ phenylephrine

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Methylin (methylphenidate) + Vicks DayQuil Cold & Flu (acetaminophen/ dextromethorphan/ phenylephrine)

Monitor/Modify Tx


methylphenidate + dextromethorphan

monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

methylphenidate + phenylephrine

monitor BP, HR: combo may incr. risk of HTN, tachycardia, other cardiovascular and CNS stimulatory effects (additive effects)

Additional Considerations

Smiley face Smiley face methylphenidate in Methylin

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some ER methylphenidate formulations (including capsule, chewable, oral suspension, ODT); combo may incr. methylphenidate release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face phenylephrine in Vicks DayQuil Cold & Flu

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face dextromethorphan in Vicks DayQuil Cold & Flu

add MAO inhibitor to Interaction Check if recent (14 days) use

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