ethinyl estradiol (contraceptive) + hepatitis B immune globulin

monitor thrombosis s/sx; use lowest hepatitis B immune globulin infusion rate possible: combo may incr. risk of thromboembolism (additive effects)

levonorgestrel (contraceptive) + hepatitis B immune globulin

monitor thrombosis s/sx, especially w/ concomitant estrogen use; use lowest hepatitis B immune globulin infusion rate possible: combo may incr. risk of thromboembolism (additive effects)

ethinyl estradiol (contraceptive) + lamotrigine

consider gradual incr. of lamotrigine maint. dose up to 2-fold, initial dose escalation unchanged; no change if also on carbamazepine, phenytoin, phenobarbital, primidone, rifampin, or ritonavir: combo may decr. lamotrigine levels, efficacy; transient incr. of lamotrigine levels, adverse effects may occur during inert tab phase (UGT induced)

ethinyl estradiol (contraceptive) + nadolol

monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

lamotrigine + nadolol

monitor HR: combo may incr. risk of bradycardia (additive effects)