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Interaction Check

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Selected Drugs Clear All

  • remove Journavx
    suzetrigine
  • remove M-End DMX
    dexbrompheniramine/ dextromethorphan/ pseudoephedrine
  • remove Ritalin LA
    methylphenidate

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face M-End DMX (dexbrompheniramine/ dextromethorphan/ pseudoephedrine) + Ritalin LA (methylphenidate)

Monitor/Modify Tx


dextromethorphan + methylphenidate

monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

pseudoephedrine + methylphenidate

monitor BP, HR: combo may incr. risk of HTN, tachycardia, CNS stimulatory effects (additive effects)

Additional Considerations

Smiley face Smiley face pseudoephedrine in M-End DMX

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face dextromethorphan in M-End DMX

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face methylphenidate in Ritalin LA

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some ER methylphenidate formulations (including capsule, chewable, oral suspension, ODT); combo may incr. methylphenidate release rate, levels, risk of adverse effects, decr. duration of efficacy

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