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Interaction Check

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Selected Drugs Clear All

  • remove American dwarf palm tree
    saw palmetto (Serenoa repens)
  • remove Subutex
    buprenorphine
  • remove Tigan
    trimethobenzamide

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx
Smiley face Smiley face Subutex (buprenorphine) + Tigan (trimethobenzamide)

Monitor/Modify Tx

buprenorphine + trimethobenzamide

monitor respiratory rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects)

Additional Considerations
Smiley face Smiley face buprenorphine in Subutex

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use
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