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Interaction Check

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Selected Drugs Clear All

  • remove Femynor
    norgestimate/ ethinyl estradiol
  • remove Kenalog
    triamcinolone topical
  • remove Luvox
    fluvoxamine
  • remove pomelo
    grapefruit (Citrus paradisi)
  • remove Zofran
    ondansetron

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Luvox (fluvoxamine) + Zofran (ondansetron)

Avoid/Use Alternative


fluvoxamine + ondansetron

use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

Smiley face Smiley face pomelo (grapefruit (Citrus paradisi)) + Zofran (ondansetron)

Avoid/Use Alternative


grapefruit + ondansetron

use alternative or monitor ECG w/ large amounts of grapefruit (>1L juice): combo may incr. risk of QT prolongation, cardiac arrhythmias (additive effects)

Monitor/Modify Tx

Smiley face Smiley face Femynor (norgestimate/ ethinyl estradiol) + pomelo (grapefruit (Citrus paradisi))

Monitor/Modify Tx


ethinyl estradiol (contraceptive) + grapefruit

monitor thrombosis s/sx, especially if oral ethinyl estradiol dose >35 mcg/day: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (GI metabolism inhibited)

Additional Considerations

Smiley face Smiley face fluvoxamine in Luvox

add MAO inhibitor to Interaction Check if recent (14 days) use

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