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Interaction Check

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Selected Drugs Clear All

  • remove glipizide/ metformin
    generic
  • remove Mounjaro
    tirzepatide
  • remove Ritalin SR
    methylphenidate

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face glipizide/metformin (generic) + Mounjaro (tirzepatide)

Monitor/Modify Tx


glipizide + tirzepatide

monitor glucose; consider decr. glipizide dose: combo may incr. risk of severe hypoglycemia (additive effects)

Additional Considerations

Smiley face Smiley face methylphenidate in Ritalin SR

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some ER methylphenidate formulations (including capsule, chewable, oral suspension, ODT); combo may incr. methylphenidate release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face tirzepatide in Mounjaro

caution advised with oral drugs, especially narrow therapeutic index; tirzepatide delays gastric emptying, may alter absorption of concomitant oral drugs

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