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Interaction Check

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Selected Drugs Clear All

  • remove Altabax
    retapamulin topical
  • remove Dasetta 1/ 35
    norethindrone/ ethinyl estradiol
  • remove Nicorette Gum
    nicotine transmucosal
  • remove Paxil CR
    paroxetine
  • remove Spiriva Respimat
    tiotropium inhaled
  • remove Taztia XT
    diltiazem

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Dasetta 1/35 (norethindrone/ ethinyl estradiol) + Taztia XT (diltiazem)

Monitor/Modify Tx


ethinyl estradiol (contraceptive) + diltiazem

monitor BP, thrombosis s/sx, especially if oral ethinyl estradiol dose >35 mcg/day: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects; may decr. antihypertensive agent efficacy (hepatic metabolism inhibited; antagonistic effects)

Additional Considerations

Smiley face Smiley face diltiazem in Taztia XT

avoid combo with beverages or products containing ethanol and Cardizem CD, Cartia XT, some generic extended-release (ER) capsules; combo may incr. diltiazem release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face nicotine in Nicorette Gum

caution advised with concomitant drugs; dose adjustments may be necessary; smoking cessation may alter pharmacokinetics or pharmacodynamics of certain drugs

Smiley face Smiley face paroxetine in Paxil CR

add MAO inhibitor to Interaction Check if recent (14 days) use

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