Selected Drugs Clear All
MultiCheck Results
- 5
Interactions
Avoid/Use Alternative |
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Tussionex PennKinetic
(chlorpheniramine/ hydrocodone) + Zomig Nasal
(zolmitriptan nasal) |
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Avoid/Use Alternativehydrocodone + zolmitriptan avoid combo if antitussive use; otherwise use alternative or monitor respiratory rate, serotonin syndrome sx, especially during initiation/titration; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, serotonin syndrome (additive effects) Caution Advisedchlorpheniramine + zolmitriptan caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Monitor/Modify Tx |
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Exparel
(bupivacaine liposomal) + Tussionex PennKinetic
(chlorpheniramine/ hydrocodone) |
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Monitor/Modify Txbupivacaine liposomal + hydrocodone monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope (additive effects) |
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Caution Advised |
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Exparel
(bupivacaine liposomal) + Goody's Powder Back & Body Pain
(acetaminophen/ aspirin) |
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Caution Advisedbupivacaine liposomal + acetaminophen caution advised: combo may incr. risk of methemoglobinemia (additive effects) |
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Goody's Powder Back & Body Pain
(acetaminophen/ aspirin) + Zomig Nasal
(zolmitriptan nasal) |
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Caution Advisedacetaminophen + zolmitriptan caution advised w/ oral acetaminophen: combo may decr. peak acetaminophen levels, delay analgesic onset, efficacy (mechanism unknown) |
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Additional Considerations |
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zolmitriptan
in Zomig Nasal
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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hydrocodone
in Tussionex PennKinetic
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use benzhydrocodone (prodrug) rapidly converted to hydrocodone; similar interactions anticipated add MAO inhibitor to Interaction Check if recent (14 days) use avoid combo with beverages or products containing ethanol and some hydrocodone extended-release (ER) capsules; combo may incr. hydrocodone release rate, levels, risk of adverse effects, including life-threatening overdose, decr. duration of efficacy |
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