Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Monitor/Modify Tx |
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imipramine
(generic) + Klonopin Wafers
(clonazepam) |
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Monitor/Modify Tximipramine + clonazepam monitor respiratory rate: combo may incr. risk of CNS and respiratory depression, psychomotor impairment; may alter seizure control (additive effects; antagonistic effects, imipramine may decr. seizure threshold) |
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imipramine
(generic) + Ongentys
(opicapone) |
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Monitor/Modify Tximipramine + opicapone monitor BP; consider decr. dose of one or both drugs: combo may incr. risk of CNS depression, psychomotor impairment, hypotension, including orthostasis, syncope (additive effects) |
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Klonopin Wafers
(clonazepam) + Ongentys
(opicapone) |
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Monitor/Modify Txclonazepam + opicapone monitor respiratory rate; consider decr. dose of one or both drugs: combo may incr. risk of CNS and respiratory depression, psychomotor impairment (additive effects) |
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Additional Considerations |
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octreotide
in Sandostatin LAR Depot
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caution advised with narrow therapeutic index drugs extensively metabolized by CYP450 liver enzymes; octreotide inhibition of growth hormone production may decr. CYP450 metabolic function, incr. levels of concomitant drugs, risk of adverse effects caution advised with oral drugs; octreotide alters nutrient absorption, may alter absorption of concomitant drugs, incr. risk of adverse effects or decr. efficacy |
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imipramine
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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