epocrates logo
epocrates logo
epocrates logo
  • 0

Interaction Check

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

  • remove Bromfed DM
    brompheniramine/ dextromethorphan/ pseudoephedrine
  • remove Femynor
    norgestimate/ ethinyl estradiol
  • remove Luvox
    fluvoxamine
  • remove Zofran
    ondansetron

multicheck MultiCheck Results - 5 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Bromfed DM (brompheniramine/ dextromethorphan/ pseudoephedrine) + Luvox (fluvoxamine)

Avoid/Use Alternative


dextromethorphan + fluvoxamine

use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

Caution Advised


brompheniramine + fluvoxamine

caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects)

Smiley face Smiley face Bromfed DM (brompheniramine/ dextromethorphan/ pseudoephedrine) + Zofran (ondansetron)

Avoid/Use Alternative


dextromethorphan + ondansetron

use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

Smiley face Smiley face Luvox (fluvoxamine) + Zofran (ondansetron)

Avoid/Use Alternative


fluvoxamine + ondansetron

use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

Monitor/Modify Tx

Smiley face Smiley face Bromfed DM (brompheniramine/ dextromethorphan/ pseudoephedrine) + Femynor (norgestimate/ ethinyl estradiol)

Monitor/Modify Tx


pseudoephedrine + ethinyl estradiol (contraceptive)

monitor BP: combo may incr. risk of HTN (additive effects)

Additional Considerations

Smiley face Smiley face fluvoxamine in Luvox

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face pseudoephedrine in Bromfed DM

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face dextromethorphan in Bromfed DM

add MAO inhibitor to Interaction Check if recent (14 days) use

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information