Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Avoid/Use Alternative |
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Ambien
(zolpidem) + Robitussin AC
(codeine/ guaifenesin) |
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Avoid/Use Alternativezolpidem + codeine avoid combo if antitussive use; otherwise monitor respiratory rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects) |
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Mono-Linyah
(norgestimate/ ethinyl estradiol) + Robitussin AC
(codeine/ guaifenesin) |
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Avoid/Use Alternativeethinyl estradiol (contraceptive) + codeine use alternative or monitor respiratory rate, withdrawal sx: combo may incr. codeine, alter active metabolite morphine levels, incr. risk of CNS and respiratory depression, psychomotor impairment, other adverse effects or decr. efficacy (hepatic metabolism inhibited, may alter production of active metabolite morphine) |
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Monitor/Modify Tx |
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Mono-Linyah
(norgestimate/ ethinyl estradiol) + Norditropin
(somatropin (recombinant)) |
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Additional Considerations |
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codeine
in Robitussin AC
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use |
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somatropin
in Norditropin
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caution advised with drugs metabolized by CYP450 liver enzymes; somatropin may increase CYP450 metabolic function, alter levels of concomitant drugs, incr. risk of adverse effects or decr. efficacy lonapegsomatropin is a prodrug of somatropin; similar interactions anticipated |
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