Selected Drugs Clear All
MultiCheck Results
- 1
Interaction
Monitor/Modify Tx |
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guanfacine
(generic) + Suboxone
(buprenorphine/ naloxone) |
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Monitor/Modify Txguanfacine + buprenorphine monitor respiratory rate, BP; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, severe hypotension, including orthostasis, syncope (additive effects) |
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Additional Considerations |
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buprenorphine
in Suboxone
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use |
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naloxone (abuse deterrent)
in Suboxone
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no pharmacologic activity when administered as directed |
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cefpodoxime
in Vantin
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cefpodoxime proxetil (prodrug) converted to cefpodoxime |
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