Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Monitor/Modify Tx |
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diazepam rectal
(generic) + Equetro
(carbamazepine) |
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Monitor/Modify Txdiazepam + carbamazepine monitor respiratory rate; use lowest effective doses and shortest duration of concomitant tx: combo may decr. diazepam levels, efficacy; may incr. risk of profound CNS and respiratory depression, psychomotor impairment (hepatic metabolism induced; additive effects) |
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diazepam rectal
(generic) + valproate sodium
(generic) |
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Monitor/Modify Txdiazepam + valproic acid monitor respiratory rate, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects) |
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Equetro
(carbamazepine) + valproate sodium
(generic) |
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Monitor/Modify Txcarbamazepine + valproic acid monitor levels of both drugs: combo may decr. valproic acid levels, efficacy; may incr. carbamazepine active metabolite levels, risk of CNS depression, psychomotor impairment, other adverse effects (UGT induced; epoxide hydrolase inhibited, additive effects) |
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Additional Considerations |
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carbamazepine
in Equetro
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add MAO inhibitor to Interaction Check if recent (14 days) use some formulations of carbamazepine contain sorbitol |
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