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Interaction Check

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Selected Drugs Clear All

  • remove Diclegis
    doxylamine/ pyridoxine
  • remove gabapentin
    generic
  • remove Lyrica
    pregabalin

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Diclegis (doxylamine/ pyridoxine) + gabapentin (generic)

Avoid/Use Alternative


doxylamine + gabapentin

avoid combo if doxylamine use for pregnancy-related nausea/vomiting, otherwise monitor respiratory rate; consider decreasing gabapentin dose: combo may increase risk of profound CNS and respiratory depression, psychomotor impairment (additive effects)

Smiley face Smiley face Diclegis (doxylamine/ pyridoxine) + Lyrica (pregabalin)

Avoid/Use Alternative


doxylamine + pregabalin

avoid combo if doxylamine use for pregnancy-related nausea/vomiting; otherwise, monitor respiratory rate: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment (additive effects)

Smiley face Smiley face gabapentin (generic) + Lyrica (pregabalin)

Avoid/Use Alternative


gabapentin + pregabalin

avoid combo: combo may increase risk of profound CNS and respiratory depression, psychomotor impairment, other adverse effects (additive effects, duplicate therapy)

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