Selected Drugs Clear All
MultiCheck Results
- 5
Interactions
Monitor/Modify Tx |
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Mibelas 24 Fe
(norethindrone/ ethinyl estradiol) + Prevalite
(cholestyramine) |
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Monitor/Modify Txethinyl estradiol (contraceptive) + cholestyramine give oral contraceptive at least 1h before or 4-6h after each cholestyramine dose: combo may decr. ethinyl estradiol levels, contraceptive efficacy (absorption decreased/delayed) norethindrone (contraceptive) + cholestyramine give oral contraceptive at least 1h before or 4-6h after each cholestyramine dose: combo may decr. norethindrone levels, contraceptive efficacy (absorption decreased/delayed) |
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Mibelas 24 Fe
(norethindrone/ ethinyl estradiol) + Prograf
(tacrolimus) |
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Monitor/Modify Txethinyl estradiol (contraceptive) + tacrolimus monitor tacrolimus levels, ECG, BP, renal fxn: combo may incr. tacrolimus levels, risk of QT prolongation, cardiac arrhythmias, HTN, nephrotoxicity, other adverse effects (hepatic metabolism inhibited, additive effects) |
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Prevalite
(cholestyramine) + Prograf
(tacrolimus) |
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Monitor/Modify Txcholestyramine + tacrolimus give oral tacrolimus at least 1h before or 4-6h after each cholestyramine dose; monitor tacrolimus levels: combo may decr. tacrolimus levels, efficacy (absorption decreased/delayed) |
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Caution Advised |
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fluticasone propionate nasal
(generic) + Prograf
(tacrolimus) |
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Caution Advisedfluticasone propionate + tacrolimus caution advised: combo may incr. risk of serious infection (additive effects) |
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Additional Considerations |
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pancuronium
in Pavulon
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Discontinued in US |
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tacrolimus
in Prograf
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monitor tacrolimus levels in combo with HCV Direct Acting Antiviral (DAA) tx; viral eradication may improve hepatic metabolic function, alter tacrolimus levels, efficacy avoid combo with beverages or products containing ethanol and tacrolimus extended-release (ER) formulations; combo may incr. tacrolimus release rate, levels, risk of adverse effects, decr. duration of efficacy |
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cholestyramine
in Prevalite
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give oral drugs at least 1h before or 4-6h after cholestyramine; bile acid sequestrant may delay or decr. absorption of concomitant oral drugs |
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