epocrates logo
epocrates logo
epocrates logo
  • 0

Interaction Check

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

  • remove clindamycin
    generic
  • remove nimodipine
    generic
  • remove spironolactone
    generic

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Monitor/Modify Tx
Smiley face Smiley face clindamycin (generic) + spironolactone (generic)

Monitor/Modify Tx

clindamycin + spironolactone

monitor renal fxn: combo may incr. risk of nephrotoxicity (additive effects)

Smiley face Smiley face nimodipine (generic) + spironolactone (generic)

Monitor/Modify Tx

nimodipine + spironolactone

monitor BP: combo may incr. nimodipine levels, risk of hypotension, other adverse effects (hepatic metabolism possibly inhibited)

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information