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Interaction Check

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Selected Drugs Clear All

  • remove Children's Triaminic Multi-Symptom Fever & Cold
    acetaminophen/ chlorpheniramine/ dextromethorphan/ phenylephrine
  • remove norethindrone acetate/ ethinyl estradiol
    generic
  • remove Pulmicort Flexhaler
    budesonide inhaled
  • remove Vicks Sinex Severe Nasal Spray
    oxymetazoline nasal

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Children's Triaminic Multi-Symptom Fever & Cold (acetaminophen/ chlorpheniramine/ dextromethorphan/ phenylephrine) + norethindrone acetate/ethinyl estradiol (generic)

Monitor/Modify Tx


acetaminophen + ethinyl estradiol (hormone replacement)

monitor thrombosis s/sx: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (mechanism unknown)

Smiley face Smiley face Children's Triaminic Multi-Symptom Fever & Cold (acetaminophen/ chlorpheniramine/ dextromethorphan/ phenylephrine) + Vicks Sinex Severe Nasal Spray (oxymetazoline nasal)

Monitor/Modify Tx


phenylephrine + oxymetazoline nasal

monitor BP: combo may incr. risk of HTN (additive effects)

Additional Considerations

Smiley face Smiley face phenylephrine in Children's Triaminic Multi-Symptom Fever & Cold

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face dextromethorphan in Children's Triaminic Multi-Symptom Fever & Cold

add MAO inhibitor to Interaction Check if recent (14 days) use

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