Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Avoid/Use Alternative |
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Fioricet with Codeine
(butalbital/ acetaminophen/ caffeine/ codeine) + nicardipine
(generic) |
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Avoid/Use Alternativebutalbital + nicardipine use alternative or monitor BP: combo may decr. nicardipine levels, efficacy (hepatic metabolism induced) codeine + nicardipine use alternative or monitor respiratory rate, BP; consider decr. codeine dose: combo may incr. codeine and active metabolite morphine levels, risk of CNS and respiratory depression, psychomotor impairment, severe hypotension (including orthostasis, syncope), other adverse effects (hepatic metabolism inhibited, may incr. production of active metabolite morphine; additive effects) Monitor/Modify Txcaffeine + nicardipine monitor BP; avoid excessive caffeine intake: combo may decr. antihypertensive agent efficacy (antagonistic effects) |
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Additional Considerations |
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codeine
in Fioricet with Codeine
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use |
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