Interaction Check

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MultiCheck Results - 4 Interactions

Monitor/Modify Tx
Aplenzin (bupropion hydrobromide) + Esgic-Plus (butalbital/ acetaminophen/ caffeine)
Monitor/Modify Tx bupropion + caffeine monitor BP; avoid excessive caffeine intake: combo may incr. risk of HTN (additive effects) Caution Advised bupropion + butalbital caution advised: combo may decr. bupropion and metabolite levels, efficacy (hepatic metabolism induced)
Aplenzin (bupropion hydrobromide) + Vicks Sinex Severe Nasal Spray (oxymetazoline nasal)
Monitor/Modify Tx bupropion + oxymetazoline nasal monitor BP: combo may incr. risk of HTN (additive effects)
Esgic-Plus (butalbital/ acetaminophen/ caffeine) + Vicks Sinex Severe Nasal Spray (oxymetazoline nasal)
Monitor/Modify Tx caffeine + oxymetazoline nasal monitor BP; avoid excessive caffeine intake: combo may incr. risk of HTN (additive effects)
Additional Considerations
bupropion in Aplenzin
caution advised with concomitant drugs if smoking cessation use; dose adjustments may be necessary; smoking cessation may alter pharmacokinetics or pharmacodynamics of certain drugs add MAO inhibitor to Interaction Check if recent (14 days) use