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Interaction Check

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Selected Drugs Clear All

  • remove acetaminophen rectal
    generic
  • remove Camrese
    levonorgestrel/ ethinyl estradiol
  • remove Hailey 1.5/ 30
    norethindrone/ ethinyl estradiol
  • remove Infumorph
    morphine sulfate
  • remove Lasix
    furosemide
  • remove Typhim Vi
    typhoid vi polysaccharide vaccine

multicheck MultiCheck Results - 8 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Camrese (levonorgestrel/ ethinyl estradiol) + Hailey 1.5/30 (norethindrone/ ethinyl estradiol)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + ethinyl estradiol (contraceptive)

avoid combo: combo may incr. risk of HTN, thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy)

levonorgestrel (contraceptive) + norethindrone (contraceptive)

avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)

Smiley face Smiley face Camrese (levonorgestrel/ ethinyl estradiol) + Lasix (furosemide)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + furosemide

use alternative or monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

Smiley face Smiley face Hailey 1.5/30 (norethindrone/ ethinyl estradiol) + Lasix (furosemide)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + furosemide

use alternative or monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

Monitor/Modify Tx

Smiley face Smiley face acetaminophen rectal (generic) + Camrese (levonorgestrel/ ethinyl estradiol)

Monitor/Modify Tx


acetaminophen + ethinyl estradiol (contraceptive)

monitor thrombosis s/sx: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (mechanism unknown)

Smiley face Smiley face acetaminophen rectal (generic) + Hailey 1.5/30 (norethindrone/ ethinyl estradiol)

Monitor/Modify Tx


acetaminophen + ethinyl estradiol (contraceptive)

monitor thrombosis s/sx: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (mechanism unknown)

Smiley face Smiley face Infumorph (morphine sulfate) + Lasix (furosemide)

Monitor/Modify Tx


morphine + furosemide

monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope; may decr. furosemide efficacy (additive effects; antagonistic effects, opioids may induce antidiuretic hormone release)

Caution Advised

Smiley face Smiley face acetaminophen rectal (generic) + Infumorph (morphine sulfate)

Caution Advised


acetaminophen + morphine

caution advised w/ oral acetaminophen: combo may decr. peak acetaminophen levels, delay analgesic onset, efficacy (absorption delayed, possibly decreased)

Additional Considerations

Smiley face Smiley face morphine in Infumorph

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some morphine extended-release (ER) capsules; combo may incr. morphine release rate, levels, risk of adverse effects, including life-threatening overdose, decr. duration of efficacy

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