Selected Drugs Clear All
MultiCheck Results
- 6
Interactions
Avoid/Use Alternative |
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Desogen
(desogestrel/ ethinyl estradiol) + tizanidine
(generic) |
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Avoid/Use Alternativeethinyl estradiol (contraceptive) + tizanidine use alternative or monitor BP, HR: combo may incr. tizanidine levels, risk of hypotension (including orthostasis, syncope), bradycardia, CNS depression, psychomotor impairment, other adverse effects (hepatic metabolism inhibited) |
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Monitor/Modify Tx |
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AndroGel
(testosterone transdermal) + Desogen
(desogestrel/ ethinyl estradiol) |
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Monitor/Modify Txtestosterone + desogestrel (contraceptive) monitor thrombosis s/sx, especially w/ concomitant estrogen use: combo may incr. risk of thromboembolism (additive effects) testosterone + ethinyl estradiol (contraceptive) monitor BP, thrombosis s/sx: combo may incr. risk of HTN, thromboembolism (additive effects) |
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AndroGel
(testosterone transdermal) + metoprolol succinate
(generic) |
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Monitor/Modify Txtestosterone + metoprolol monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects) |
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Desogen
(desogestrel/ ethinyl estradiol) + metoprolol succinate
(generic) |
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Monitor/Modify Txethinyl estradiol (contraceptive) + metoprolol monitor BP: combo may incr. metoprolol levels, risk of hypotension, bradycardia, AV block, other adverse effects; may decr. antihypertensive agent efficacy (hepatic metabolism inhibited; antagonistic effects) |
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metoprolol succinate
(generic) + tizanidine
(generic) |
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Monitor/Modify Txmetoprolol + tizanidine monitor BP: combo may incr. risk of hypotension, including orthostasis, syncope (additive effects) |
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Additional Considerations |
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metoprolol
in metoprolol succinate
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avoid combo with beverages or products containing ethanol and metoprolol extended-release (ER) sprinkle; combo may incr. metoprolol release rate, levels, risk of adverse effects, decr. duration of efficacy |
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