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Interaction Check

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Selected Drugs Clear All

  • remove Eraxis
    anidulafungin
  • remove Iophen C-NR
    codeine/ guaifenesin
  • remove SAM-e
    SAMe
  • remove Viread
    tenofovir disoproxil

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Iophen C-NR (codeine/ guaifenesin) + SAM-e (SAMe)

Avoid/Use Alternative


codeine + SAMe

use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects)

Additional Considerations

Smiley face Smiley face codeine in Iophen C-NR

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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