Interaction Check

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MultiCheck Results - 2 Interactions

Avoid/Use Alternative
BC Powder (aspirin/ caffeine) + Zanaflex (tizanidine)
Avoid/Use Alternative caffeine + tizanidine use alternative or monitor BP, HR: combo may incr. tizanidine levels, risk of hypotension (including orthostasis, syncope), bradycardia, CNS depression, psychomotor impairment, other adverse effects (hepatic metabolism inhibited)
Monitor/Modify Tx
aripiprazole (generic) + Zanaflex (tizanidine)
Monitor/Modify Tx aripiprazole oral + tizanidine monitor BP: combo may incr. risk of CNS depression, psychomotor impairment, hypotension, including orthostasis, syncope (additive effects)
Additional Considerations
aripiprazole oral in aripiprazole
drug interactions apply only to oral aripiprazole forms; see other aripiprazole products for potentially relevant interactions aripiprazole is a substrate of CYP2D6 and CYP3A4; drug interaction guidance may vary with CYP450 inhibitors if patient is CYP2D6 poor metabolizer (PM)