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Interaction Check

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Selected Drugs Clear All

  • remove Bumex
    bumetanide
  • remove Dilaudid
    hydromorphone

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Bumex (bumetanide) + Dilaudid (hydromorphone)

Monitor/Modify Tx


bumetanide + hydromorphone

monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope; may decr. bumetanide efficacy (additive effects; antagonistic effects, opioids may induce antidiuretic hormone release)

Additional Considerations

Smiley face Smiley face hydromorphone in Dilaudid

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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