Selected Drugs Clear All
MultiCheck Results
- 3
Interactions
Avoid/Use Alternative |
||
|
buspirone
(generic) + Dilaudid
(hydromorphone) |
||
Avoid/Use Alternativebuspirone + hydromorphone use alternative or monitor respiratory rate, serotonin syndrome sx, especially during initiation/titration; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, serotonin syndrome (additive effects) |
||
Monitor/Modify Tx |
||
|
buspirone
(generic) + perphenazine
(generic) |
||
Monitor/Modify Txbuspirone + perphenazine consider decr. dose of one or both drugs: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
||
|
Dilaudid
(hydromorphone) + perphenazine
(generic) |
||
Monitor/Modify Txhydromorphone + perphenazine monitor respiratory rate, BP; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, severe hypotension (including orthostasis, syncope), severe constipation, paralytic ileus, urinary retention (additive effects) |
||
Additional Considerations |
||
|
hydromorphone
in Dilaudid
|
||
|
consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use |
||
|
buspirone
|
||
|
add MAO inhibitor to Interaction Check if recent (14 days) use |
||