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Interaction Check

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Selected Drugs Clear All

  • remove Nicorette Gum
    nicotine transmucosal
  • remove Sotyktu
    deucravacitinib
  • remove Tenivac
    tetanus/ diphtheria toxoids (Td)

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Sotyktu (deucravacitinib) + Tenivac (tetanus/ diphtheria toxoids (Td))

Monitor/Modify Tx


deucravacitinib + diphtheria/ tetanus vaccine

if possible, vaccinate at least 2wk before starting deucravacitinib tx; otherwise, consider post-immunization titer check or revaccination after immunocompetence restored: combo may result in inadequate vaccine response (immunosuppressive effects)

Additional Considerations

Smiley face Smiley face nicotine in Nicorette Gum

caution advised with concomitant drugs; dose adjustments may be necessary; smoking cessation may alter pharmacokinetics or pharmacodynamics of certain drugs

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