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Interaction Check

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Selected Drugs Clear All

  • remove Blisovi Fe 1.5/ 30
    norethindrone/ ethinyl estradiol
  • remove Trokendi XR
    topiramate

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Blisovi Fe 1.5/30 (norethindrone/ ethinyl estradiol) + Trokendi XR (topiramate)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + topiramate

use additional non-hormonal or alternative contraception during and x28 days after topiramate tx, especially w/ topiramate doses >200 mg/day: combo may decr. ethinyl estradiol levels, contraceptive efficacy (hepatic metabolism induced)

norethindrone (contraceptive) + topiramate

use additional non-hormonal or alternative contraception during and x28 days after topiramate tx, especially w/ topiramate doses >200 mg/day: combo may decr. norethindrone levels, contraceptive efficacy (hepatic metabolism induced)

Additional Considerations

Smiley face Smiley face topiramate in Trokendi XR

beverages or products containing ethanol are contraindicated within 6h of topiramate extended-release (ER) capsules administration; combo may incr. topiramate release rate, levels, risk of adverse effects, decr. duration of efficacy

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