Selected Drugs Clear All
MultiCheck Results
- 2
Interactions
Avoid/Use Alternative |
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erythromycin ethylsuccinate
(generic) + Lonsurf
(trifluridine/ tipiracil) |
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Avoid/Use Alternativeerythromycin + trifluridine use alternative or monitor ECG: combo may incr. risk of QT prolongation, cardiac arrhythmias (additive effects) |
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Monitor/Modify Tx |
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digoxin
(generic) + erythromycin ethylsuccinate
(generic) |
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Monitor/Modify Txdigoxin + erythromycin monitor digoxin levels, HR; decr. digoxin frequency or dose by 30-50%: combo may incr. digoxin levels, risk of bradycardia, AV block, other adverse effects (P-gp-mediated transport inhibited) |
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Additional Considerations |
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digoxin
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monitor digoxin levels more frequently when starting, adjusting, or stopping other drugs, including short-term therapies, OTC drugs, and/or herbal supplements monitor electrolytes more frequently with concomitant drugs, OTC drugs, and/or herbal supplements that may lead to electrolyte abnormalities, resulting in potential incr. risk of digoxin toxicity, cardiac arrhythmias |
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