Selected Drugs Clear All
MultiCheck Results
- 24
Interactions
Avoid/Use Alternative |
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Frova
(frovatriptan) + selegiline
(generic) |
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Avoid/Use Alternativefrovatriptan + selegiline use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome, CNS depression, psychomotor impairment (additive effects) |
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Frova
(frovatriptan) + sodium oxybate
(generic) |
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Avoid/Use Alternativefrovatriptan + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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Levsin
(hyoscyamine) + sodium oxybate
(generic) |
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Avoid/Use Alternativehyoscyamine + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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prochlorperazine maleate
(generic) + sodium oxybate
(generic) |
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Avoid/Use Alternativeprochlorperazine + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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Robaxin
(methocarbamol) + sodium oxybate
(generic) |
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Avoid/Use Alternativemethocarbamol + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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selegiline
(generic) + sodium oxybate
(generic) |
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Avoid/Use Alternativeselegiline + oxybate use alternative or monitor resp. rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, hypotension, syncope (additive effects) |
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Monitor/Modify Tx |
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Emgality (galcanezumab-gnlm)
(galcanezumab) + Frova
(frovatriptan) |
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Monitor/Modify Txgalcanezumab + frovatriptan monitor BP: combo may incr. risk of HTN (additive effects) |
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Emgality (galcanezumab-gnlm)
(galcanezumab) + lakritze
(licorice (Glycyrrhiza glabra)) |
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Monitor/Modify Txgalcanezumab + licorice monitor BP w/ large amounts of licorice: combo may incr. risk of HTN (additive effects) |
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ferrous sulfate
(generic) + Levsin
(hyoscyamine) |
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Monitor/Modify Txferrous sulfate + hyoscyamine separate admin. by 1h: combo may decr. hyoscyamine levels, efficacy (absorption decreased via chelation) |
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Frova
(frovatriptan) + lakritze
(licorice (Glycyrrhiza glabra)) |
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Monitor/Modify Txfrovatriptan + licorice monitor BP w/ large amounts of licorice: combo may incr. risk of HTN (additive effects) |
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prochlorperazine maleate
(generic) + selegiline
(generic) |
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Monitor/Modify Txprochlorperazine + selegiline monitor BP: combo may decr. selegiline efficacy; may incr. risk of CNS depression, psychomotor impairment, hypotension, incl. orthostasis (antagonistic effects; additive effects) |
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prochlorperazine maleate
(generic) + Urecholine
(bethanechol) |
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Monitor/Modify Txprochlorperazine + bethanechol monitor BP: combo may incr. risk of hypotension, incl. orthostasis; may decr. efficacy of both drugs (additive effects; antagonistic effects) |
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selegiline
(generic) + Urecholine
(bethanechol) |
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Monitor/Modify Txselegiline + bethanechol monitor BP: combo may incr. risk of hypotension, incl. orthostasis (additive effects) |
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Caution Advised |
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agnus castus
(chasteberry (Vitex agnus-castus)) + prochlorperazine maleate
(generic) |
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Caution Advisedchasteberry + prochlorperazine caution advised: combo may decr. prochlorperazine efficacy (antagonistic effects, chasteberry exerts dopaminergic effects) |
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Frova
(frovatriptan) + Levsin
(hyoscyamine) |
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Caution Advisedfrovatriptan + hyoscyamine caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Frova
(frovatriptan) + prochlorperazine maleate
(generic) |
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Caution Advisedfrovatriptan + prochlorperazine caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Frova
(frovatriptan) + Robaxin
(methocarbamol) |
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Caution Advisedfrovatriptan + methocarbamol caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Levsin
(hyoscyamine) + prochlorperazine maleate
(generic) |
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Caution Advisedhyoscyamine + prochlorperazine caution advised: combo may incr. risk of CNS depression, psychomotor impairment, anticholinergic adverse effects; may decr. prochlorperazine efficacy (additive effects; antagonistic effects) |
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Levsin
(hyoscyamine) + Robaxin
(methocarbamol) |
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Caution Advisedhyoscyamine + methocarbamol caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Levsin
(hyoscyamine) + selegiline
(generic) |
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Caution Advisedhyoscyamine + selegiline caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Levsin
(hyoscyamine) + Urecholine
(bethanechol) |
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Caution Advisedhyoscyamine + bethanechol caution advised: combo may decr. efficacy of both drugs (antagonistic effects) |
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prochlorperazine maleate
(generic) + Robaxin
(methocarbamol) |
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Caution Advisedprochlorperazine + methocarbamol caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Robaxin
(methocarbamol) + selegiline
(generic) |
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Caution Advisedmethocarbamol + selegiline caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects) |
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Robaxin
(methocarbamol) + Urecholine
(bethanechol) |
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Caution Advisedmethocarbamol + bethanechol caution advised: combo may decr. efficacy of both drugs (antagonistic effects) |
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Additional Considerations |
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nicotine
in Nicotrol NS
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caution advised w/ concomitant drugs; dose adjustments may be necessary; smoking cessation may alter pharmacokinetics or pharmacodynamics of certain drugs |
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hyoscyamine
in Levsin
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caution advised w/ concurrent oral drugs requiring rapid onset; hyoscyamine delays gastric emptying, may alter absorption of concomitant oral drugs |
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selegiline
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add fluoxetine to Interaction Check if recent (5wk) use |
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lamivudine
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avoid combo of lamivudine oral solution w/ oral products containing sorbitol; may give lamivudine tab formulation or monitor virologic response more frequently if combo cannot be avoided; sorbitol may decr. bioavailability of lamivudine, resulting in decr. levels, efficacy |
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