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Interaction Check

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Selected Drugs Clear All

  • remove Acanya
    clindamycin/ benzoyl peroxide topical
  • remove Acuvail
    ketorolac ophthalmic
  • remove ketoprofen
    generic
  • remove Morphabond ER
    morphine sulfate
  • remove RectiCare Advanced Cream
    lidocaine/ phenylephrine/ mineral oil/ petrolatum topical
  • remove Xopenex HFA
    levalbuterol inhaled
  • remove Xulane
    norelgestromin/ ethinyl estradiol transdermal

multicheck MultiCheck Results - 5 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Acuvail (ketorolac ophthalmic) + ketoprofen (generic)

Monitor/Modify Tx


ketorolac ophthalmic + ketoprofen

monitor bleeding s/sx: combo may incr. risk of postop ocular bleeding (additive effects)

Smiley face Smiley face ketoprofen (generic) + Xopenex HFA (levalbuterol inhaled)

Monitor/Modify Tx


ketoprofen + levalbuterol inhaled

monitor BP: combo may incr. risk of HTN (additive effects)

Smiley face Smiley face ketoprofen (generic) + Xulane (norelgestromin/ ethinyl estradiol transdermal)

Monitor/Modify Tx


ketoprofen + ethinyl estradiol (contraceptive)

monitor BP, thrombosis s/sx; use lowest effective ketoprofen dose, shortest effective tx duration: combo may incr. risk of HTN, thromboembolism (additive effects)

ketoprofen + norelgestromin (contraceptive)

monitor thrombosis s/sx, especially w/ concomitant estrogen use; use lowest effective ketoprofen dose, shortest effective tx duration: combo may incr. risk of thromboembolism (additive effects)

Smiley face Smiley face Xopenex HFA (levalbuterol inhaled) + Xulane (norelgestromin/ ethinyl estradiol transdermal)

Monitor/Modify Tx


levalbuterol inhaled + ethinyl estradiol (contraceptive)

monitor BP: combo may incr. risk of HTN (additive effects)

Additional Considerations

Smiley face Smiley face morphine in Morphabond ER

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some morphine extended-release (ER) capsules; combo may incr. morphine release rate, levels, risk of adverse effects, including life-threatening overdose, decr. duration of efficacy

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