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Interaction Check

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Selected Drugs Clear All

  • remove Mitigare
    colchicine
  • remove norelgestromin/ ethinyl estradiol transdermal
    generic
  • remove Tri-Estarylla
    norgestimate/ ethinyl estradiol

multicheck MultiCheck Results - 4 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Mitigare (colchicine) + norelgestromin/ethinyl estradiol transdermal (generic)

Avoid/Use Alternative


colchicine + ethinyl estradiol (contraceptive)

CV RISK REDUCTION: consider monitoring CK, myopathy s/sx; GOUT or FMF: use alternative or consider decr. colchicine dose during and x14 days after ethinyl estradiol use: combo may incr. colchicine levels, risk of myopathy, rhabdomyolysis, other life-threatening toxicity (hepatic metabolism inhibited)

Smiley face Smiley face Mitigare (colchicine) + Tri-Estarylla (norgestimate/ ethinyl estradiol)

Avoid/Use Alternative


colchicine + ethinyl estradiol (contraceptive)

CV RISK REDUCTION: consider monitoring CK, myopathy s/sx; GOUT or FMF: use alternative or consider decr. colchicine dose during and x14 days after ethinyl estradiol use: combo may incr. colchicine levels, risk of myopathy, rhabdomyolysis, other life-threatening toxicity (hepatic metabolism inhibited)

Smiley face Smiley face norelgestromin/ethinyl estradiol transdermal (generic) + Tri-Estarylla (norgestimate/ ethinyl estradiol)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + ethinyl estradiol (contraceptive)

avoid combo: combo may incr. risk of HTN, thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy)

norelgestromin (contraceptive) + norgestimate (contraceptive)

avoid combo: combo may incr. risk of thromboembolism, other adverse effects (additive effects, duplicate therapy)

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