aprepitant + brexpiprazole

if aprepitant 3-day regimen, decr. brexpiprazole dose 75% if CYP2D6 poor metabolizer or if also combined w/ moderate or strong CYP2D6 inhibitor; aprepitant single dose-regimen OK: combo may incr. brexpiprazole levels, risk of adverse effects (hepatic metabolism inhibited)